چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | فرید مسعود |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | کمیته تحقیقات دانشجویی |
| کد مقاله | 67946 |
| عنوان فارسی مقاله | ارزیابی اثر بخشی محلول موضعی گیاهی در درمان آلوپسی آندروژنتیک و مقایسه آن با ماینوکسیدیل 5٪: یک مطالعه دو سوکور، تصادفی شده، کارآزمایی بالینی |
| عنوان لاتین مقاله | Evaluating the Efficacy of Topical Herbal Solution on the Treatment of Androgenetic Alopecia and Comparison with Minoxidil 5%: A Double-Blind, Randomized, Clinical Trial Study |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | International Student Congress Of Medical Sciences (ISCOMS) |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Netherlands |
| شهر محل برگزاری کنگره/ همایش | Groningen |
| سال انتشار/ ارائه شمسی | 1398 |
| سال انتشار/ارائه میلادی | 2019 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1398/03/13 الی 1398/03/17 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://iscoms.com/wp-content/uploads/2019/06/Book-of-Abstracts-ISCOMS-2019.pdf |
| آدرس علمی (Affiliation) نویسنده متقاضی | Tabriz University of Medical Science, Student Research Committee, Pharmacy faculty, Tabriz, Iran, Islamic Republic of |
| نویسنده | نفر چندم مقاله |
|---|---|
| فرید مسعود | اول |
| یوسف جوادزاده | دوم |
| حمیده عظیمی علمداری | سوم |
| جواد شکری | چهارم |
| سولماز اثناعشری | پنجم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Topical Herbal Solution, Androgenetic Alopecia, Hair loss |
| خلاصه مقاله | Introduction: Androgenetic alopecia (AGA) is caused by miniaturization of androgen-sensitive hair follicles and common form of scalp hair loss. Finasteride and Minoxidil have been approved by the American Food and Drug Administration (FDA) for the treatment of AGA. But these have a lot of side effects. Herbal extracts have more mechanism for treating AGA, fewer side effects and patient satisfaction. The aim of this study was to examine the efficacy and safety of topical herbal solution in males with AGA. Materials & Methods: We conducted a randomized, double-blind, parallel-group clinical trial at the dermatology department in Sina hospital. Male volunteers aged between 18 and 50 years with mild to moderate AGA were randomly assigned (1:1), via computer-generated randomization, to receive either herbal or Minoxidil5% topical solution. The first group received herbal solution every evening + Minoxidil 5% every morning for 12 to 24 weeks, while the second group received only Minoxidil 5% for the same period. After a baseline visit, patients were evaluated by clinical examination, photographic documentation, a self-assessment test, and measuring hair diameter every month. Written informed consent was obtained from all participants prior to entry. Results: Analysis of the two groups showed significant differences and highly positive response to treatment in the first group compared to the second group. In the first group, hair diameter increased compared to the baseline visit. Specifically, after a few weeks, hair loss was stopped only in the first group. The patients were satisfied with the herbal solution and during this period, no significant adverse events were reported Conclusion: These results suggest that the new herbal solution is responsible for a significant improvement of AGA and could be an alternative treatment in patients who didn’t have an efficiency of standard medications or cannot tolerate those side-effects. To our knowledge, this herbal solution for the first time covers all three major causes of AGA, including the 5α-reductase enzyme, androgen receptors, and paracrine agents that affecting dermal papilla. Therefore it acts with the triple mechanism, different from the already existing therapies |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Book-of-Abstracts-ISCOMS-2019_Part1.pdf | 1398/04/25 | 368749 | دانلود |
| Certificate.pdf | 1398/04/25 | 1914318 | دانلود |
| Letter of Acceptance Massoud.pdf | 1398/04/25 | 354566 | دانلود |
| Ticket.pdf | 1398/05/02 | 137826 | دانلود |
| Visa.pdf | 1398/05/02 | 2284329 | دانلود |
| IMG-20190717-WA0003.jpg | 1398/05/02 | 49529 | دانلود |
| New Invitation Letter.pdf | 1398/05/02 | 368990 | دانلود |
| 1-Edited.docx | 1398/05/06 | 14317 | دانلود |
| 2-Edited.docx | 1398/05/06 | 15754 | دانلود |
