چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Abstract Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease with unknown origin. The disease causes a broad spectrum of signs and symptoms in a majority of body organs. Due to several factors like damage to mucosal surfaces and defect in complement systems, these patients are at a great risk of infections with opportunistic pathogens. Aim of the work: To evaluate the nasal carriage of Staphylococcus aureus, rate of Methicillinresistant S. aureus (MRSA) and its correlation with relapse in lupus patients. Patients and methods: In an analytical-descriptive study, 80 patients (65 female and 15 male) with SLE attending the rheumatology clinics of Tabriz University of medical sciences were selected. Nasal mucosa specimens of the patients were taken and incubated in appropriate culture environment. All of the patients were followed for 1 year and the relapse of the disease was evaluated. Results: The mean age of the patients was 25.35± 5.87 years. The mean disease duration was 3.66 ± 2.27 years and the mean SLE disease activity index (SLEDAI) was 6.40 ±2.84. Thirty-nine out of 80 patients (48.75%) were positive for S. aureus in the nasal mucosa. Although no significant difference in SLEDAI was observed between the patients with nasal carriage of S. aureus and those without, the two groups were significantly different in the relapse and complement levels. Conclusion: These results indicate that relapse of SLE in patients having S. aureus in their nasal mucosa is higher than in patients without. 2014 Production and hosting by Elsevier B. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهرزاد حاج علیلوی بناب | اول |
| امیر قربانی حق جو | دوم |
| علیرضا خبازی اسکویی | سوم |
| حامد ولی زاده | چهارم |
| سینا رئیسی | پنجم |
| آلکا حسنی | ششم |
| مجتبی ورشوچی فرد | هفتم |
| سوسن کلاهی | هشتم |
| محمد رضا جعفری نخجوانی | نهم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 7.1-s2.0-S1110116414000611-main.pdf | 1398/04/25 | 371614 | دانلود |
