| Objective: Manipulating the intestinal microbiota for the benefit of the mental health is a concept that has become
widely acknowledged. Prebiotics, the nondigestible nutrients, can proliferate intrinsic beneficial gut bacteria, and so
provide an alternative strategy for effectively altering the enteric ecosystem, and then brain function. This review
summarizes findings from studies using prebiotics to improve mental health and psychological disorders.
Methods: Pub Med, Google Scholar, Scopus, and Science Direct databases were searched by using “prebiotics”,
“psychological disorder”, “mood disorder”, “depression”, “anxiety”, “stress”, “sleep”, and “cognition” for the studies
aiming the application of prebiotics and the beneficial effects of them in mental health and psychological disorders’
control and/or treatment.
Results: Prebiotic consumption improved psychological and biological measures of mental disorders such as
depression, anxiety, and stress in individuals with mood disorder. Overall, the results showed that, through modulating
the gut microbiota composition, prebiotics can beneficially affect mental health, modulate psychological disorders, and
improve cognitive function and sleep/wake cycle disruptions.
Discussion: Prebiotics can improve mental health, mood, and psychological function. Habitual diets rich in dietary
prebiotics would be linked to reduced risk of developing symptoms of psychological disorders; however, additional
studies are necessary. |