The relationship of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in peripheral blood with ST-segment resolution and the clinical outcomes of STEMI patients receiving thrombolytic therapy
The relationship of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in peripheral blood with ST-segment resolution and the clinical outcomes of STEMI patients receiving thrombolytic therapy
نویسندگان: صمد غفاری باویل , احمد سپرهم , پونه پاشاپور
کلمات کلیدی: neutrophil, lymphocyte, platelet, myocardial infarction
نشریه: 55460 , 1 , 57 , 2019
| نویسنده ثبت کننده مقاله |
احمد سپرهم |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
67740 |
| عنوان فارسی مقاله |
The relationship of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in peripheral blood with ST-segment resolution and the clinical outcomes of STEMI patients receiving thrombolytic therapy |
| عنوان لاتین مقاله |
The relationship of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in peripheral blood with ST-segment resolution and the clinical outcomes of STEMI patients receiving thrombolytic therapy |
| ناشر |
3 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Introduction. One of the inflammatory factors affecting the prognosis of myocardial infarction
is the high level of neutrophil count in the blood. In this study, we investigated the relationship of
neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in peripheral blood
with ST-segment resolution and clinical outcomes of patients with ST-elevation myocardial infarction
(STEMI) receiving thrombolytic therapy.
Methods. This cross-sectional study was conducted on the patients referring to the emergency
department in Tabriz, Iran who were diagnosed with STEMI and began receiving treatment with
reteplase. The patients were asked questions to gather information about their demographic
characteristics as well as their risk factors, level of response to thrombolytic therapy, etc. For all of
the patients, electrocardiogram (ECG) was recorded and different blood tests were performed upon
their admission to the emergency department and the obtained data were fed into SPSS Version 19 to
explore the possible relationships among different variables.
Results. The findings of this study revealed that there is no significant relationship between
either NLR or PLR of patients suffering from myocardial infarction and their level of response to
thrombolytic therapy. Moreover, no significant relationship was observed between NLR or PLR of
these patients and their ejection fraction. However, the results indicated that NLR and PLR associated
with an increase in the incidence rate of major adverse cardiac events (MACE) in STEMI patients.
Conclusion. The results of this study indicated that NLR and PLR are directly associated with
the rate of in-hospital major adverse effects following STEMI irrespective of the ST resolution |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Pashapour paper.pdf | 1398/04/13 | 294651 | دانلود |