Determining the Frequency of Macroamylasemia in Patients with Hyperamylasemia using PEG Precipitation Method
Determining the Frequency of Macroamylasemia in Patients with Hyperamylasemia using PEG Precipitation Method
نویسندگان: طلا پورلک , بهروز شکوهی گوگانی , امیر واحدی , بهاره مهر آموز , پرهام معروفی , طناز پورلک
کلمات کلیدی: Acute abdomen, Acute pancreatitis, Amylase, Cholecystitis, Pancreatitis
نشریه: 19694 , 5 , 12 , 2018
| نویسنده ثبت کننده مقاله |
طلا پورلک |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
بیماری های بافت همبند |
| کد مقاله |
67639 |
| عنوان فارسی مقاله |
Determining the Frequency of Macroamylasemia in Patients with Hyperamylasemia using PEG Precipitation Method |
| عنوان لاتین مقاله |
Determining the Frequency of Macroamylasemia in Patients with Hyperamylasemia using PEG Precipitation Method |
| ناشر |
7 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Introduction: The term acute abdomen refers to severe and
sudden abdominal pain requiring urgent reorganisation. One
of the factors causing acute abdomen is acute pancreatitis,
which needs immediate measurements. Acute pancreatitis is
also associated with increased levels of serum amylase and
lipase. Increased serum amylase also appears under other
conditions including macroamylasemia and would result in
misdiagnosis.
Aim: This study aimed to investigate the frequency of
macroamylasemia in hyperamylasemia patients using
Polyethylene Glycol (PEG) precipitation method.
Materials and Methods: In this cross-sectional study, 100
patients with high serum amylase who received healthcare
services in Tabriz Imam Reza Hospital from 2014 to 2015 were
included. Presence of macroamylase was evaluated in patients
using PEG sedimentation method. Collected data were analysed
using SPSS software version 17 and chi-square test, as well as
independent sample t-test were carried out. The significance
level was set at <0.05.
Results: Of 100 patients, 63% were male and 37% were female
and their mean age was 50.2±0.7 years. The mean level of
serum amylase was 740.4±277.567 U/L and the mean level of
serum amylase after PEG precipitation was 578±240.05 U/L.
No significant correlation was found (p=0.478). In this study, the
frequency of macroamylasemia was 4 (4%) and the frequency
of real hyperamylasemia was equal to 96 (96%). The mean level
of serum amylase after PEG precipitation was higher in real
hyperamylasemia patients than in macroamylasemia patients and
a significant association was observed in this regard (p<0.001).
Conclusion: The current study showed that a high percentage
of hyperamylasemia patients experience macroamylasemia.
Regarding the findings and the significance of this issue, it is
recommended to consider the diagnosis of macroamylasemia as
one of the best approaches to prevent undertaking unnecessary
diagnostic procedures and treatments. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 41-Determining the Frequency of Macroamylasemia in Patients.pdf | 1398/04/09 | 463169 | دانلود |