Frequency of mecA, pvl, arcA, speG genes in Staphylococcus aureus isolated from Burn Wounds in Tabriz, Iran
Frequency of mecA, pvl, arcA, speG genes in Staphylococcus aureus isolated from Burn Wounds in Tabriz, Iran
نویسندگان: نسترن اسماعیل زاده , آلکا حسنی , طاهره پیرزاده , مهین آهنگر اسکوئی , لیلا دهقانی , دل آرا لاغوثی , جاوید صادقی
کلمات کلیدی: Antibiotic Susceptibility Patterns, Burn Wound Infection, Minimum Inhibitory Concentration, Staphylococcus aureus
نشریه: 38984 , 2 , . , 2018
| نویسنده ثبت کننده مقاله |
دل آرا لاغوثی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
عوامل اجتماعی موثر بر سلامت |
| کد مقاله |
67443 |
| عنوان فارسی مقاله |
Frequency of mecA, pvl, arcA, speG genes in Staphylococcus aureus isolated from Burn Wounds in Tabriz, Iran |
| عنوان لاتین مقاله |
Frequency of mecA, pvl, arcA, speG genes in Staphylococcus aureus isolated from Burn Wounds in Tabriz, Iran |
| ناشر |
8 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Background: Burn wounds provide a proper position for bacterial growth and are more persistent richer sources of infection than other
wounds. Staphylococcus aureus (S. aureus) is one of the most commonly isolated pathogens in burn wound infections. Methods: One
hundred S. aureus isolates were collected from burn wound infections. Identification of S. aureus was performed by phenotypic and
molecular methods. The Kirby-Bauer and agar dilution methods were performed for determination of antibiotic susceptibility patterns.
Polymerase chain reaction (PCR) was carried out for detection of mecA, pvl, nuc, arcA and speG genes. Results: Methicillin resistant S.
aureus (MRSA) was detected in 21 % of isolates by mecA gene PCR and phenotypic methods. All isolates were negative for arcA and
speG genes. All of isolates were susceptible to linezolid, vancomycin and mupirocin. The resistance rate to erythromycin and
clindamycin were high. Conclusion: Our findings showed that S. aureus isolates have high-level resistance to antimicrobial agents and
that appropriate antibiotic therapy, based on the antibiotic susceptibility pattern, is essential to ensure a good result. Thus, strict
consideration for S. aureus infection and proper usage of antibiotic policy are recommended in decreasing the incidence and occurrence
of multidrug resistant S. aureus infections in burn wound infections in this hospital. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| frequency-of-meca-pvl-arca-speg-genes-in-staphylococcus-aureus-isolated-from-burn-wounds-in-tabriz.pdf | 1398/03/28 | 174222 | دانلود |