| of Anesthesiology and Critical Care (Autumn 2016); 2(4): 239-242 http://aacc.tums.ac.ir 239
RESEARCH ARTICLE
Sore throat is one of the major complications of tracheal intubation after general
anesthesia. Harpagophytum is an herbal medicine, the anti-inflammatory and analgesic effects of which
have been demonstrated in various studies. We studied the effects of single dose Harpagophytum one
hour before tracheal intubation, to prevent the sore throat after extubation.
In a randomized clinical trial, 60 patients who had undergone general and urologic surgeries at
Imam Reza hospital in Tabriz, Iran, since March to July 2015 that required tracheal intubation, were
included in the study. The patients were randomly divided into two groups (case group 30 patients and
control group 30 patients). In the case group, one hour before anesthesia, one Teltonal capsule (480 mg)
was given to the patients. For the control group of patients, the empty capsule of Teltonal was given.
After patients regained consciousness, the severity of sore throat was scaled and recorded by VAS scale
after 2, 6 and 24 hours of the surgery.
Severity and incidence of sore throat after tracheal intubation were not significantly different
between case and control groups. Also, no side effects of Harpagophytum were observed in the case
group.
Administration of Harpagophytum with the single dose of 480 mg one hour before the
anesthesia and intubation did not decrease the sore throat severity and incidence. |