| Background: Considering the high success rate of osseointegration, there is ever-increasing use of dental implants. The
mechanisms and biologic response of peri-implant tissues are
different depending on the biocompatibility of the implant material. The aim of this study was to compare the proinflammatory
cytokine levels in the gingival crevicular fluid (GCF) around
dental implants with ceramic and titanium abutments.
Materials and methods: All the patients with dental implants
referring to two private offices of two prosthodontists from June
to August 2016 were examined in relation to implant health, and
eligible subjects, based on inclusion criteria, were included in
this study with a slit-mouth design. In this context, on one side
titanium implants and, on the other side, ceramic implants were
used. Samples were collected from the peri-implant sulcus in
each patient and sent to the immunology laboratory for determination of interleukin (IL)-6 and IL-1β proinflammatory cytokine
levels using an enzyme-linked immunosorbent assay kit. Data
were analyzed with Statistical Package for the Social Sciences
version 16. Statistical significance was set at p<0.05.
Results: The results showed lower levels of IL-1β and IL-6 in
the GCF around ceramic abutments compared with titanium
implants. In addition, statistical comparison between IL-6 and
IL-1β levels showed higher levels of IL-6 around titanium and
ceramic abutments compared with IL-1β levels. |