Nasal and extra nasal MRSA colonization in hemodialysis patients of north-west of Iran
Nasal and extra nasal MRSA colonization in hemodialysis patients of north-west of Iran
نویسندگان: بهروز نقیلی حکم آبادی , احد بازمانی , مجتبی ورشوچی فرد , لیلا رهبرنیا , فاطمه روانبخش گاوگانی , علیرضا دهناد , محمدحسین غفاری اقدم
کلمات کلیدی: : S. aureus, MRSA colonization, Hemodialysis patients
نشریه: 5038 , 260 , 12 , 2019
| نویسنده ثبت کننده مقاله |
لیلا رهبرنیا |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
بیماری های عفونی و گرمسیری |
| کد مقاله |
66840 |
| عنوان فارسی مقاله |
Nasal and extra nasal MRSA colonization in hemodialysis patients of north-west of Iran |
| عنوان لاتین مقاله |
Nasal and extra nasal MRSA colonization in hemodialysis patients of north-west of Iran |
| ناشر |
7 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح دو – PubMed |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Objectives: Methicillin resistant Staphylococcus (S.) aureus colonization is one of the main causes of serious infections
in hemodialysis patients. This cross-sectional study was performed to examine prevalence of MRSA colonization and
evaluation of risk factors in hemodialysis patients. A total of 560 swab samples from nasal, the skin around catheter
and throat were collected from 231 hemodialysis patients in Tabriz. The standard biochemical tests were used for
identifcation of S. aureus isolates. Antimicrobial susceptibility profle was determined against 11 antibiotics by the disk
difusion method. Phenotypic test of S. aureus was performed using novobiocin 30 μg/disc, and methicillin sensitivity
test was performed by cefoxitin 30 μg/disc.
Results: Overall, 50.65% (118/231) hemodialysis patients were positive for S. aureus which 34.93% (80/231) of
patients were MRSA carriage. The MRSA colonization in patients with a catheter (44.06%) was more than individuals
utilizing a fstula (24.57%, p=0.030). Among sampling sites, the highest MRSA was related to nasal samples (30.70%,
p<0.00001). Extra nasal colonization of S. aureus was observed in 12.71% patients. The highest rates of resistance were
observed against ampicillin (93.98%) and the highest sensitivity was against linezolid antibiotic (5.42%). These fndings
highlight the necessity of prophylaxis against S. aureus in individuals under dialysis. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| ravanbakhsh.pdf | 1398/02/25 | 948040 | دانلود |