Effect of non-surgical periodontal treatment on transferrin serum levels in patients with chronic periodontitis

Effect of non-surgical periodontal treatment on transferrin serum levels in patients with chronic periodontitis


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: معصومه فرامرزی , محمد تقی چیت سازی , عدیله شیرمحمدی , نازیلا پاشازاده

کلمات کلیدی: Transferrin; chronic periodontitis; inflammation; dental scaling; root planing

نشریه: 19913 , 3 , 10 , 2016

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نویسنده ثبت کننده مقاله معصومه فرامرزی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده دندانپزشکی
کد مقاله 66806
عنوان فارسی مقاله Effect of non-surgical periodontal treatment on transferrin serum levels in patients with chronic periodontitis
عنوان لاتین مقاله Effect of non-surgical periodontal treatment on transferrin serum levels in patients with chronic periodontitis
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background. Transferrin is a negative acute phase protein, which decreases during inflammation and infection. The aim of the present investigation was to evaluate changes in the transferrin serum levels subsequent to non-surgical treatment of chronic periodontal disease. Methods. Twenty patients with chronic periodontitis and 20 systemically healthy subjects without periodontal disease, who had referred to Tabriz Faculty of Dentistry, were selected. Transferrin serum levels and clinical periodontal parameters (pocket depth, clinical attachment level, gingival index, bleeding index and plaque index) were measured at baseline and 3 months after non-surgical periodontal treatment. Data were analyzed with descriptive statistical methods (means ± standard deviations). Independent samples t-test was used to compare transferrin serum levels and clinical variables between the test and control groups. Paired samples t-test was used in the test group for comparisons before and after treatment. Statistical significance was set at P < 0.05. Results. The mean transferrin serum level in patients with chronic periodontitis (213.1 ± 9.2 mg/dL) was significantly less than that in periodontally healthy subjects (307.8 ± 11.7 mg/dL). Three months after periodontal treatment, the transferrin serum level increased significantly (298.3 ± 7.6 mg/dL) and approached the levels in periodontally healthy subjects (P < 0.05). Conclusion. The decrease and increase in transferrin serum levels with periodontal disease and periodontal treatment, respectively, indicated an inverse relationship between transferrin serum levels and chronic periodontitis.

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نویسنده نفر چندم مقاله
معصومه فرامرزیسوم
محمد تقی چیت سازیدوم
عدیله شیرمحمدیاول
نازیلا پاشازادهششم

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