Evaluation of Salivary Levels of Plasminogen Activator Inhibitor-2 in Patients with Moderate Generalized Chronic Periodontitis: A CaseControl Study
Evaluation of Salivary Levels of Plasminogen Activator Inhibitor-2 in Patients with Moderate Generalized Chronic Periodontitis: A CaseControl Study
نویسندگان: حسین اسلامی , همایون دولتخواه , میلاد غنی زاده , پریسا فلسفی , الهام احسنی
کلمات کلیدی: Periodontics; Chronic Periodontitis; Plasminogen Activators; Saliva.
نشریه: 27086 , 1 , 18 , 2018
| نویسنده ثبت کننده مقاله |
حسین اسلامی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده دندانپزشکی |
| کد مقاله |
66796 |
| عنوان فارسی مقاله |
Evaluation of Salivary Levels of Plasminogen Activator Inhibitor-2 in Patients with Moderate Generalized Chronic Periodontitis: A CaseControl Study |
| عنوان لاتین مقاله |
Evaluation of Salivary Levels of Plasminogen Activator Inhibitor-2 in Patients with Moderate Generalized Chronic Periodontitis: A CaseControl Study |
| ناشر |
6 |
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بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Objective: To compare salivary levels of PAI-2 in patients with moderate generalized
chronic periodontitis before and after treatment and healthy subjects. Material and
Methods: The present case-control study evaluated patients with generalized moderate
chronic periodontitis (the case group) and subjects with healthy gingiva (the control
group). The healthy subjects were evaluated once and the cases were evaluated twice
(before and after treatment) by collecting their salivary samples. ELISA technique was
used to determine PAI-2 salivary levels. Data were analyzed with the use of SPSS 17.
The level of significance was set at 5%. Results: The mean salivary levels of PAI-2 in
the case and control groups were 45.63 ± 8.63 and 22.01 ± 9.77 ng, respectively
(p<0.0001). In addition, PAI-2 salivary levels in the case group subjects after treatment
was 27.43 ± 5.79 ng, which was lower than that before treatment (45.63 ± 8.63 ng)
(p<0.0001). The mean salivary level of PAI-2 in subjects with periodontitis after
treatment (27.43 ± 5.79) was not significantly different from that in healthy subjects
(22.01 ± 9.77) (p>0.05). Conclusion: The salivary levels of PAI-2 in patient with
moderate generalized chronic periodontitis were higher than these in healthy subjects.
However, the salivary levels of PAI-2 decreased in the case group subjects after
treatment, with no significant difference from the healthy subjects. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| PAI_2.pdf | 1398/02/23 | 231472 | دانلود |