Efficacy of Photodynamic Therapy as an Adjunct to Full-mouth Root Planing in the Treatment of Periodontitis Assessed by Real-time PCR: A Microbiological and Clinical Study

Efficacy of Photodynamic Therapy as an Adjunct to Full-mouth Root Planing in the Treatment of Periodontitis Assessed by Real-time PCR: A Microbiological and Clinical Study


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دانشگاه علوم پزشکی تبریز
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نویسندگان: محمد تقی چیت سازی , عدیله شیرمحمدی , مسعود شیرمحمدی , اتابک کاشفی مهر

کلمات کلیدی: Chronic periodontitis, photochemotherapy, periodontal disease/therapy, randomized controlled trial.

نشریه: 0 , 1 , 7 , 2015

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نویسنده ثبت کننده مقاله اتابک کاشفی مهر
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات لثه و دندان
کد مقاله 66742
عنوان فارسی مقاله Efficacy of Photodynamic Therapy as an Adjunct to Full-mouth Root Planing in the Treatment of Periodontitis Assessed by Real-time PCR: A Microbiological and Clinical Study
عنوان لاتین مقاله Efficacy of Photodynamic Therapy as an Adjunct to Full-mouth Root Planing in the Treatment of Periodontitis Assessed by Real-time PCR: A Microbiological and Clinical Study
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق) J Periodontal Implant Dent
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح چهار – سایر سایت های تخصصی
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background and aims. The aim of this investigation was to compare clinical and microbiological effectiveness of adjunctive photodynamic therapy (PDT) in the treatment of periodontitis. Materials and methods. Twenty-four subjects (14 women and 10 men) diagnosed with moderate to severe chronic periodontitis underwent scaling and root planing (SRP). One tooth in each quadrant (probing depth >4 mm) was selected for combined PDT and SRP (PDT group) with the contralateral tooth (SRP group), as a control site (SRP-treated site). Clinical assessment was carried out at baseline and 1 and 3 month later. Microbial assessment was carried out by real-time PCR. Periodontal probing depth (PPD) was considered as the primary outcome. Results. Baseline PPDs were 4.86±0.77 and 4.04±0.65 in the SRP and PDT groups, respectively (P>0.05), which decreased to 3.65±0.58 in the SRP and 3.86±0.56 in the PDT groups after one month and to 3.20±0.68 in the SRP and 3.34±0.56 in the PDT groups three months later. Although values decreased significantly in both groups after one (P=0.001 in the SRP and P=0.001 in the PDT groups) and three months (P=0.001 in the SRP and P=0.001 in the PDT groups) the inter-group differences were not significant after one (P=0.25) and three months (P=0.51). Clinical measurements showed significant decreases after one and three months at both sites, without inter-group differences, except for bleeding on probing after one (P=0.004) and three months (P=0.0001). Conclusion. Subgingival application of PDT combined with scaling and root planing could not improve clinical and microbiological results.

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نویسنده نفر چندم مقاله
محمد تقی چیت سازیاول
عدیله شیرمحمدیدوم
مسعود شیرمحمدیسوم
اتابک کاشفی مهرچهارم

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PDT SRP.pdf1398/02/21181556دانلود