چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | داود خضرلو |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پیراپزشکی |
| کد مقاله | 66713 |
| عنوان فارسی مقاله | PET Radionuclides Characteristics in the Prognosis and Diagnosis of Glioma |
| عنوان لاتین مقاله | PET Radionuclides Characteristics in the Prognosis and Diagnosis of Glioma |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | 17امین کنگره علوم پرتونگاری |
| نوع کنگره / همایش | ملی |
| کشور محل برگزاری کنگره/ همایش | |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1398 |
| سال انتشار/ارائه میلادی | 2019 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1398/02/03 الی 1398/02/06 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | www.icr2019.ir |
| آدرس علمی (Affiliation) نویسنده متقاضی | 1. Department of Radiology, Paramedical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| داود خضرلو | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background: Early diagnosis of glioma have an important role in management of treatment. PET provides additional insight beyond MRI into the biology of gliomas which can be used for noninvasive grading, tumor infiltration, post-treatment monitoring and prognostication. In this study, the performance of commonly used Radionuclides for glioma imaging with PET is surveyed and compared. Materials and Methods: In this study, published articles with the keywords “PET radionuclide”, “glioma” were searched from the scientific databases and then the results were analysis Results: Currently, the most important commercial radiopharmaceuticals used in PET imaging are in two categories: Radionuclides of glucose synthesis such as fluorodeoxyglucose (FDG), and amino acid based Radionuclides, including: Fluoroethyl L Thymidine (FLT), methyl methionine carbonate (C-MET), Fluoroethylthirosine (FET) and dihydroxy fluoro-L-phenylalanine (FDOPA). FDG radiopharmaceuticals is not suitable for intracranial imaging, the sensitivity and specificity reorted 53% and 55 % respectively. Amino acid based Radionuclides have less uptake than FDG in the normal brain tissue. FLT is strongly correlated with Ki67 proliferation biomarker. Its sensitivity is 91% in all glioma grades and for grade 3, 4 it is about 100%. Sensitivity of FET, MET and FDOPA are similar and about 95%, but there have a high False Positive cases because of the uptake in fractures, infections and hemorrhage Conclusion: FLT is recommended as a specific radiotracer in glioma. There is not still appropriate technique for identification of the PET active volumes, so it seems PET cannot be yet replaced by MRI. |
| کلمات کلیدی | Glioma, PET imaging, PET Radionuclide |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Article2.pdf | 1398/02/18 | 1015104 | دانلود |
| Header.pdf | 1398/02/18 | 304815 | دانلود |
