| Objective: To evaluate the effect of Anaheal (Bromelain) drug on the periodontal
clinical indices in nonsurgical periodontal treatment of patients with chronic
periodontitis. Material and Methods: In this double blind clinical trial, 80 patients with
chronic moderate periodontitis and a healthy systemic status were chosen, and divided
into two 40-subject groups. Thereafter, the standard treatment of periodontitis
including scaling and root planning in one session by the unit operator was performed
for all patients. Eventually, one group of the patients was administered Bromelain
medication (500-mg capsule twice a day) one hour before food, while the other group
was given placebo. Four and eight weeks after the treatment, the clinical periodontal
indicators were measured and recorded in both groups. The data were assessed using
descriptive statistics and analytical test methods (Mann-U-Whitney and Chi-square). P
value less than 0.05 was considered statistically significant. Results: Gingival index,
probing depth and plaque index before the treatment were similar in both groups
(Anaheal and placebo). However, four and eight weeks after the treatment, the three
studied indices were significantly lower in the Anaheal group as compared to the
placebo (p<0.05). The index of bleeding on probing was also similar before the
treatment and four weeks after the treatment in both groups. However, eight weeks
after the treatment, this index was significantly lower in the Anaheal group as compared
to the placebo group (p<0.05). Conclusion: Administration of oral Anaheal medication
after nonsurgical periodontal treatments reduced all the clinical periodontal indices
among patients with chronic periodontitis as compared to the control group. Therefore,
it can be a suitable substitute for the common oral industrial antibiotics. |