| Abstract – Objective: There are several reports related to the incidence of bladder cancer (BC)
from various geographical locations of Iran. Nevertheless, no comprehensive systematic review has
conducted in this regard. Therefore, the present systematic review and meta-analysis carried out
to estimate the incidence rate of BC among Iranian people.
Patients and Methods: This systematic review was done based on the Preferred Reporting Items
for Systematic Reviews and Meta-Analysis (PRISMA) in October 2017. A search was performed in five
international database (Medline/PubMed, Scopus, Embase, ISI/ Web of Science, and Google Scholar),
and four national databases (Scientific Information Database, MagIran, Barakat Knowledge Network
System, and IranDoc). The incidence rate of BC was calculated using random-effect model.
Results: An aggregate of 226 papers was obtained in the primary search of the databases. After
further refinement of the retrieved studies, 29 studies were included. The age-standardized rate of
BC was 10.92, 95% CI (9.88-11.96) and, 2.80, 95% CI (2.47-3.13) in males and females, respectively.
Conclusions: The incidence of BC was lower in Iran compared to other parts of the world.
However, more investigations are needed to outline the exact incidence rate and the trend of BC
among Iranian population. |