چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Insulin is one of the most important peptide hormones with a critical role in the control of human blood glucose level. Any changes in insulin secretion level can be resulted in various diseases including diabetes, kidney failure, obesity, neurodegenerative disease and myocardial infarctions. Thus, ultrasensitive and specific recognition of insulin is crucial for early stage diagnosis and treatment of diseases. This review summarizes the trends on the use of advanced nanomaterials towards biosensing of insulin. In comparison with the conventionally used materials in sensing applications, nanomaterials can enhance the sensitivity of methods because of their exponentially increase in the surface-to-volume ratio. This feature of the nanomaterials is the main factor for designing of the point-of-care (POC) devices. Categorization and analyzing of the materials trends not only highlight the favorable features of each material but also can guide the future studies trends to the most potentially materials. Therefore, various type of nanomaterials including carbon, gold, silver, magnetic, polymer, silica and metal based materials with different biosensing techniques such as optical, electrochemical and quartz crystal microbalance for insulin detection was discussed in this review. We report most recent advances in insulin detection from Jan 2010 to Feb 2019 with discussions on their advantages and limitations. The analytical figures of merit of the developed methods are also evaluated. |
| نویسنده | نفر چندم مقاله |
|---|---|
| جعفر سلیمانی | دوم |
| سجاد عزیزی خواجه | سوم |
| مریم خوب نسب جعفری | چهارم |
| ابوالقاسم جویبان | پنجم |
| محمد حسن زاده محله | ششم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 182.pdf | 1398/02/12 | 1308991 | دانلود |
