چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| nsufficient vitamin D might -have a role in it's incidence. This study evaluated the effects of vitamin D supplementation on lipid profiles and oxidative/anti-oxidative indices in marginal vitamin D status patients with diabetic nephropathy. Methods: For the current paralleled, randomized, double-blinded, placebo-controlled clinical trial, 50 diabetic nephropathy patients with marginal serum vitamin D were selected. Intervention group received 1,25-dihydroxycholecalciferol (50000 IU/week, n ¼ 25), and placebo group (n ¼ 25) received an identical placebo, for 8 weeks. Lipid profiles (LDL, HDL, TG and TC) and oxidative/anti-oxidative markers (TAC, SOD, CAT, GPX and MDA) were measured. Results: Vitamin D supplementation significantly increased vitamin D status in the intervention group, compared to the control group (P ¼ 0.001). The reductions in the serum levels of TG, LDL and TC were significant (P ¼ 0.04, P ¼ 0.006 and P ¼ 0.02, respectively) in the intervention group. The changes in oxidative/anti-oxidative markers and HDL levels were not significant after intervention. Conclusion: In conclusion, vitamin D supplementation for 8 weeks among diabetic nephropathy patients has beneficial effects on serum vitamin D status and dyslipidemia. |
| نویسنده | نفر چندم مقاله |
|---|---|
| ملیحه برزگری | اول |
| پروین سربخش | دوم |
| مجید مبصری | سوم |
| حمید نوشاد عباسپور | چهارم |
| اسری اسفندیاری | پنجم |
| بهرام پورقاسم گرگری | هفتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| The effects of vitamin D supplementation on lipid profiles and oxidative indices among diabetic nephropathy patients with marginal vitamin D status1-s2.0-S1871402118304399-main.pdf | 1398/02/10 | 284492 | دانلود |
