| خلاصه مقاله | Prognostic value of high EZH2 expression in patients with colorectal cancer in East
Azerbaijan, Iran
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139P Prognostic value of high EZH2 expression in patients with colorectal cancer in East Azerbaijan, Iran
Z Sanaat, R Dolatkhah, N Gholami
Annals of Oncology, Volume 29, Issue suppl_9, 1 November 2018, mdy431.050, https://doi.org/10.1093/annonc/mdy431.050
Published: 25 November 2018
... in colorectal cancer (CRC), but there have only been limited findings about its overexpression with prognosis in CRC. We therefore aimed to study the relationship
between EZH2 expression and clinicopathologic variables in CRC. Methods: We retrieved the archived histological samples for immunohistochemistry...
Journal Article
Extract
Background: It has been consistently reported that enhancer of zeste homolog 2 (EZH2) is expressed in colorectal cancer (CRC), but there
have only been limited ndings about its overexpression with prognosis in CRC. We therefore aimed to study the relationship between
EZH2 expression and clinicopathologic variables in CRC.
Methods: We retrieved the archived histological samples for immunohistochemistry from patients with CRC who were followed-up
between April 2009 and February 2017. The outcomes of interest were the overall survival (OS) and the disease-free survival (DFS).
Results: We included 100 patients with CRC (mean age 57.39 ± 13.52 years, range 21–83 years).... |