Propionibacterium acnes Infection in Disc Material and Different Antibiotic Susceptibility in Patients With Lumbar Disc Herniation
Propionibacterium acnes Infection in Disc Material and Different Antibiotic Susceptibility in Patients With Lumbar Disc Herniation
نویسندگان: فیروز صالحپور , جواد آقازاده , فرهاد میرزایی , سید احمد ناصری علوی
کلمات کلیدی: Propionibacterium acnes, lumbar disc herniation, low back pain, antibiotics
نشریه: 16182 , 2 , 13 , 2019
| نویسنده ثبت کننده مقاله |
سید احمد ناصری علوی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
66490 |
| عنوان فارسی مقاله |
Propionibacterium acnes Infection in Disc Material and Different Antibiotic Susceptibility in Patients With Lumbar Disc Herniation |
| عنوان لاتین مقاله |
Propionibacterium acnes Infection in Disc Material and Different Antibiotic Susceptibility in Patients With Lumbar Disc Herniation |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Background: Low back pain is an important, worldwide clinical problem from which human populations are
suffering. It has been suggested that Propionibacterium acnes is associated with low back pain. The objective of this
clinical study is to evaluate the P. acnes infection in the disc material and antibiotic susceptibility in patients with disc
herniation.
Methods: A total of 120 patients with disc herniation surgery were enrolled in the study. The samples were excited
during discectomy and then cultured in both anaerobic and aerobic incubations. Minimum inhibitory concentration
(MIC) was performed for determination of antibiotic susceptibility.
Results: Of 120 samples, 60 (50%) samples were positive for microorganisms. Disc herniation was at the level of
L4-L5 in 63 cases and L5-S1 in 57 cases.
Conclusions: According to the results and presence of P. acnes in more than 35% of the cultured samples, the
presence of P. acnes in lumbar disc herniation is a suspected element leading to this condition. After analysis of the
antibiotics, the lowest MIC value was identified for amoxicillin, ciprofloxacin, erythromycin, rifampicin, tetracycline,
vancomycin; the moderate MIC value was for fusidic acid; and the highest MIC value was for gentamicin and
trimethoprim. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 6019.full.pdf | 1398/01/31 | 183783 | دانلود |
| tozihat.docx | 1398/01/31 | 11650 | دانلود |