Bone Status Based on Biomarkers in Hemodialysis Patients

Bone Status Based on Biomarkers in Hemodialysis Patients


چاپ صفحه
پژوهان
صفحه نخست سامانه
چکیده مقاله
چکیده مقاله
نویسندگان
نویسندگان
دانلود مقاله
دانلود مقاله
دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: محمد رضا اردلان , المیرا مستفیدی

کلمات کلیدی: Aluminum, Bone Specific Alkaline Phosphatase, Intact Parathyroid Hormone

نشریه: 10302 , 2 , 37 , 2015

اطلاعات کلی مقاله
hide/show

نویسنده ثبت کننده مقاله محمد رضا اردلان
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات کلیه
کد مقاله 66440
عنوان فارسی مقاله Bone Status Based on Biomarkers in Hemodialysis Patients
عنوان لاتین مقاله Bone Status Based on Biomarkers in Hemodialysis Patients
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق) Medical Journal of Tabriz University of Medical Sciences and Health Services
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح چهار – Index Copernicus
آدرس لینک مقاله/ همایش در شبکه اینترنت

خلاصه مقاله
hide/show

Background and Objectives: Kidney Disease has been known to be associated with bone abnormalities as early as 1883.Despite of the emergence of new and more inclusive terms; low turnover and high turnover definition still are useful definitions. Aluminum toxicity also is a great threat among these patients. Materials and Methods: The study was started on 30 patients recruited from several hemodialysis (HD) units in Tabriz. Six patients left the study and only 24 patients completed their work up (10 female and 14 males) Immunoradiometric assay was used to measure the bone specific alkaline phosphatase (BAP) and intact parathyroid hormone (i PTH). Serum Aluminum was studied by atomic absorption Results: In 8 patients (8/24, 33%) serum level of iPTH was lower than 150pg/ml, and in 14 patients (14/24, 58%) serum BAP levels was lower than 27 U/L, but only in 5 patients(5/24, 20%) the combination of low iPTH (<150 ng/ml) and low BAP (<27 U/L) was present. serum aluminum of lower than <60 ng/ml is considered normal in HD patients. We had 21 patients (21/24, 87%) with serum Aluminum level above this defined limit. Conclusion: This preliminary study at first revealed us the probable percentage of 20% for low turnover bone disease among our patients. Secondly and more importantly disclosed the high rate of aluminum exposure in our dialysis population

نویسندگان
hide/show

نویسنده نفر چندم مقاله
محمد رضا اردلانچهارم
المیرا مستفیدیدوم

لینک دانلود مقاله
hide/show

نام فایل تاریخ درج فایل اندازه فایل دانلود
61.pdf1398/02/07512825دانلود