Relation between exhaled nitric oxide and left ventricular performance in chronic hemodialysis patients
Relation between exhaled nitric oxide and left ventricular performance in chronic hemodialysis patients
نویسندگان: خلیل انصارین , مهرنوش طوفان تبریزی , حسین نامدار , جلال اعتمادی خیاوی , محمد علی محجل شجاع , کامیار قابیلی
کلمات کلیدی: Echocardiography; exhaled nitric oxide; hemodialysis; left ventricular function
نشریه: 29307 , 1 , 36 , 2014
| نویسنده ثبت کننده مقاله |
خلیل انصارین |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات سل و بیماری های ریوی |
| کد مقاله |
66336 |
| عنوان فارسی مقاله |
Relation between exhaled nitric oxide and left ventricular performance in chronic hemodialysis patients |
| عنوان لاتین مقاله |
Relation between exhaled nitric oxide and left ventricular performance in chronic hemodialysis patients |
| ناشر |
8 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Introduction: End-stage renal disease is the most debilitating condition for patients with renal diseases. Cardiovascular disease is the leading cause of death in these patients. It has been shown that nitric oxide (NO) increases in renal failure and hemodialysis patients and could be correlated with cardiovascular diseases in this population. Objectives: To investigate the relation between exhaled nitric oxide (eNO) and left ventricular performance in chronic hemodialysis patients. Methods: In this prospective study, eNO was measured in 20 chronic hemodialysis patients (13 males and 7 females with the mean age of 45.20 +/- 14.99 years). Left ventricular findings were studied by conventional and Doppler echocardiography. eNO correlation with the echocardiographic parameters was evaluated. Results: The median eNO was 11.65 ppb (range: 1.9-29.9 ppb). eNO was positively correlated with left ventricular ejection fraction (rho = 0.561, p = 0.01) and negatively correlated with left ventricular end systolic volume (rho = -0.451, p = 0.046), isovolumic relaxation time (rho = -0.448, p = 0.047) and myocardial performance index (rho = -0.587, p = 0.007). Conclusion: There is a positive correlation between eNO and left ventricular performance in chronic hemodialysis patients. Therefore, eNO may play an important role in pathophysiology of cardiac involvement in these patients. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 9.png | 1398/01/19 | 72792 | دانلود |