Gender differences in health-related quality of life among patients with colorectal cancer

Gender differences in health-related quality of life among patients with colorectal cancer


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دانشگاه علوم پزشکی تبریز
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نویسندگان: دل آرا لاغوثی

کلمات کلیدی: Keywords: Quality of life, EORTC QLQ-C30, Colorectal cancer, Gender difference.‎

نشریه: 41835 , 3 , 10 , 2019

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نویسنده ثبت کننده مقاله دل آرا لاغوثی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه عوامل اجتماعی موثر بر سلامت
کد مقاله 66319
عنوان فارسی مقاله Gender differences in health-related quality of life among patients with colorectal cancer
عنوان لاتین مقاله Gender differences in health-related quality of life among patients with colorectal cancer
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق) Journal of Gastrointestinal Oncology
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background: Evidence has shown that colorectal cancer survivors, especially women have a ‎lower health-related quality of life (HRQOL). This study aimed to assess the GOL of ‎colorectal cancer survivors as well as gender-related differences in the quality of life of ‎colorectal cancer patients in Northwest of Iran.‎ Methods: This cross-sectional study was conducted in East Azarbijaban. All patients aged ‎‎≥18 years, and diagnosed with Colorectal cancer regardless of its stage and plans for ‎treatment, and also referred to teaching hospitals within a two years' time frame of 2014 -‎‎2016, were included in this study. The Persian version of the EORTC QLQ-C30 ‎questionnaire was completed for each patient by two trained interviewers. Student t-test and ‎χ2 test were used to analyze Gender differences among patients, clinical-epidemiological ‎characteristics, as well as the scores of QLQ-C30 dimensions. Multiple‏ ‏linear regression ‎models were used to assess the relationship between the score of the EORTC QLQ-C30 ‎questionnaire and gender.‎ Results: overall 303 patients (166 male, 137 female) with a diagnosis of colorectal cancer ‎were included in the study. The mean age of participants was 58.16± 13.58 years. The mean ‎scores of physical (b= -14.80, P= 0.001) and social functioning (b= -9.14, P= 0.038) of ‎women with colorectal cancer were more negatively affected than men with colorectal cancer. ‎In addition, women had a higher mean score in pain (b=10.74, P= 0.022) and fatigue ‎‎(b=12.53, P= 0.007) symptom subscales in comparison to men. Based on the results of ‎multivariate linear regression analysis, gender, occupation, and adjuvant therapy can be ‎considered as the independent and strong predictor factors of functional scale in our ‎colorectal cancer patients.‎ ‎ Conclusion:‎‏ ‏Women appear to be more affected than men by impaired physical and social ‎functioning after the development of cancer, and they reported more fatigue and pain than ‎men. Therefore, it might be advisable to consider strategies to improve the HRQOL in ‎women.‎

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دل آرا لاغوثیاول

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