| Breast cancer is a common disease in women, and is
increasing in frequency in both developed and
developing countries [1]. Although the main cause
is, as yet, fully established, aetiology is likely to be
multifactorial, one of the most significant being alternations in certain genes such as tumour suppressor
genes, growth adjusting genes, and oncogenes.
Some of these are single nucleotide polymorphisms
(SNPs), most of which are detrimental and so are
likely to play a role in susceptibility to cancer and
deterioration of the disease [2]. Chronic inflammation, together with intrinsic properties of malignant
cells and other pathophysiological processes can
promote tumour formation and its further development. Different factors involved in chronic inflammation can stimulate cell growth, invasion, mutagenesis
and angiogenesis |