Preventive effects of oxytocin and oxytocin receptor in breast cancer pathogenesis
Preventive effects of oxytocin and oxytocin receptor in breast cancer pathogenesis
نویسندگان: محمدرضا علی وند
کلمات کلیدی: breast cancer•gene expression•oxytocin•oxytocin receptor
نشریه: 27038 , 1 , 16 , 2019
| نویسنده ثبت کننده مقاله |
محمدرضا علی وند |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
66094 |
| عنوان فارسی مقاله |
Preventive effects of oxytocin and oxytocin receptor in breast cancer pathogenesis |
| عنوان لاتین مقاله |
Preventive effects of oxytocin and oxytocin receptor in breast cancer pathogenesis |
| ناشر |
8 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Aim:Modificationsofoxytocin(OT)concentrationandOTreceptor(OXTR)expressionlevelhavedifferent effects on breast cancer-derived cells. This study was conducted to evaluate OT variation in breast cancer patients and to evaluate OXTR expression changes in breast cancer tissues. Methods: The plasma concentrations of OT in both breast cancer patients and healthy individuals’ samples were assessed. Then, OXTR variations were assessed in both cancerous and noncancerous breast tissues. Results: OT had an increase in breast cancer patients and expression of OXTR in contralateral breast is more than cancerous tissues. Conclusion: Despite the high levels of OT concentration in breast cancer patients, it seems that a lower expression of OXTR in cancerous tissues can be effective in the breast cancer progression |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| pme-2018-0009_2( pornour).pdf | 1397/12/16 | 453776 | دانلود |