چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| امین کامرانی | اول |
| مجید احمدی | دوم |
| مهدی یوسفی | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background: Being one of the most common health threatening challenges, cancer is forcing scientists to conduct different studies to cure and manage the disease. Despite traditional therapies, new therapeutic approaches including immunotherapy are considered to be alternatives. Methods: ROR-1 is a tyrosine kinase receptor being expressed in different cancer cells and contains extracellular and intracellular parts that are good targets for new therapeutic strategies. Immunotherapy strategies utilized against ROR-1 include specific monoclonal antibodies and modified T cells (CART cell). This review aims at studying different types of cancer immunotherapy targeting ROR-1. Conclusion: Presently, human and chimeric antibodies, as well as CARs T cells and modified T cells Bi-specific T cell engagers (BiTEs) are used to target the ROR marker while testing on cancer cell lines. Today, cancer immunotherapy can be regarded as a new and effective way of controlling and treating different types of cancer. |
| کلمات کلیدی | Keywords: receptor tyrosine kinas like orphan, immunotherapy, cancer |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| govahi oral.pdf | 1397/11/30 | 570898 | دانلود |
| govahi sherkat.pdf | 1397/11/30 | 568846 | دانلود |
| ketapche kongere.png | 1397/11/30 | 708460 | دانلود |
| 2.docx | 1397/12/04 | 15714 | دانلود |
| 1.docx | 1397/12/04 | 14367 | دانلود |
