| Biosensors have been commonly used in biomedical diagnostic tools in recent years, because of a wide range of
application, such as point-of-care monitoring of treatment and disease progression, drug discovery, commonly
use food control, environmental monitoring and biomedical research. Additionally, development of DNA biosensors
has been increased enormously over the past few years as confirmed by the large number of scientific
publications in this field. A wide range of techniques can be used for the development of DNA biosensors, such as
DNA nano-machines and various signal amplification strategies. This article selectively reviews the recent advances
in DNA base biosensors with various signal amplification strategies for detection of cancer DNA and
microRNA, infectious microorganisms, and toxic metal ions. |