چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Multiple sclerosis (MS) is a chronic disease that leads to disability and reduced function in young adults. Depression is one of the common mood disorders in MS that affects these patients quality of life. Several treatments including drug therapy and psychotherapy have been used for the treatment of depression and fatigue. In this study we aim to evaluate the role of Sertraline in prevention of depression and QOL improvement in MS patients. In this randomized clinical trial, 60 patients with MS were selected and randomly allocated into groups receiving Sertraline and placebo. 25 patients in the intervention group and 21 patients in the control group completed the study. Both groups were evaluated for milton depression score, quality of life according to SF-36 questionnaire before the study, at the end of the first, third and sixth month. There was no significant difference according to baseline findings between groups. Three and 6 months after treatment intervention group compared to control group had significantly lower depression (p<0.001) and higher quality of life (p<0.001). Serial changes in the above mentioned variables in time in intervention group was significantly better than control group (p<0.001). Results of current study showed that treatment with sertraline in patients with MS can prevent depression occurrence and improve quality of life in these patients. |
| نویسنده | نفر چندم مقاله |
|---|---|
| سپیده هریزچی قدیم | اول |
| شیدا شعفی | سوم |
| مازیار هاشمیلر | چهارم |
| همایون صادقی بازرگانی | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Sertraline_effectiveness_in_prevention_o(3).pdf | 1397/11/06 | 261108 | دانلود |
