Solubility of lamotrigine in 2-propanol + water mixtures at T = (293.2 to 313.2) K
Solubility of lamotrigine in 2-propanol + water mixtures at T = (293.2 to 313.2) K
نویسندگان: ابوالقاسم جویبان , محمد برزگر جلالی , الهه رحیم پور , هما رضائی
کلمات کلیدی: Solubility
Lamotrigine
2-propanol
Binary solvent mixture
Cosolvency models
Solution thermodynamics
Preferential solvation
نشریه: 18106 , 592–599 , 278 , 2019
| نویسنده ثبت کننده مقاله |
الهه رحیم پور |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کاربردی دارویی |
| کد مقاله |
65737 |
| عنوان فارسی مقاله |
Solubility of lamotrigine in 2-propanol + water mixtures at T = (293.2 to 313.2) K |
| عنوان لاتین مقاله |
Solubility of lamotrigine in 2-propanol + water mixtures at T = (293.2 to 313.2) K |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| The aims of this study were to investigate the solubility behavior of lamotrigine (LTG) in the binary mixed solvents of 2-propanol and water within the temperature range of 293.2–313.2 K and correlate the experimental
values by some mathematical models including the van't Hoff equation, Yalkowsky model, Jouyban-Acree
model, Jouyban-Acree-van't Hoff model and the modified Wilson model. The density of the saturated solutions
of LTG in various solvent compositions and temperatures was also measured and the results were represented
mathematically with Jouyban-Acree model. Furthermore, the apparent thermodynamic properties of LTG dissolving, as well as the preferential solvation, in the investigated mixed solvents were calculated and the details
were discussed. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Solubility of lamotrigine in 2-propanol + water mixtures at.pdf | 1397/11/04 | 802154 | دانلود |