A review of the health hazards of artificial sweeteners: are they safe?

A review of the health hazards of artificial sweeteners: are they safe?


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نویسندگان: وحیده ابراهیم زاده عطاری , محمد رضا اردلان , آیدا مالک مهدوی

کلمات کلیدی: artificial sweeteners, non-nutritive sweeteners, side effect, adverse effect, obesity, metabolic, nephrotoxic, gut microbiome

نشریه: 28307 , supplement 2 , 20 , 2018

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله آیدا مالک مهدوی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه بیماری های بافت همبند
کد مقاله 65724
عنوان فارسی مقاله A review of the health hazards of artificial sweeteners: are they safe?
عنوان لاتین مقاله A review of the health hazards of artificial sweeteners: are they safe?
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Review Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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The increasing prevalence of obesity and diabetes mellitus has led to an increased production and consumption of artificially sweetened foods all over the world. Artificial sweeteners are high-intensity sweeteners which contribute no calorie. As a result, most of these foods may be sold with a “healthy” or “diet” labeling; however, there have been lots of controversy regarding their safety and adverse health effects. Therefore, the present article review aimed to summarize the results of most relevant studies concerning side effects of artificial sweeteners. Accordingly, a search of several databases was performed to identify all related manuscripts from 1980 to 2016. As a result, most of the available animal studies demonstrated that chronic exposure to artificial sweeteners led to increased body weight, impairment of glucose and insulin homeostasis, alteration in gut microbiota, neurobehavioral effects and also induction of kidney injury and cancer. However, the existing clinical and epidemiologic data are partly inconsistent to make a definitive conclusion regarding some of those adverse effects. In conclusion, consumers should be aware of the potential side effects of artificial sweeteners and it may be recommended that only minimal amounts of NNS could be consumed.

نویسندگان
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نویسنده نفر چندم مقاله
وحیده ابراهیم زاده عطاریاول
محمد رضا اردلاندوم
آیدا مالک مهدویسوم

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