چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Background: Bacterial superantigens are potent T cell activators that can have acute or chronic effects on the centralnervoussystem. Objectives: In this study, the role of enterotoxins, exfoliative toxins and toxic shock syndrome toxin of StaphylococcusaureuswasinvestigatedinMSpatientsandhealthynasalcarriers. Methods: Three-hundred fifty nasal swabs were collected from healthy nasal carriers (n=210) and MS (n=140) patients. Staphylococcus aureus superantigens were detected by multiplex PCR. Antimicrobial susceptibilitypatternwasperformedusingdiskdiffusionmethod. Results: The highest rates of nasalcolonization were seen in MS patients (46.42%). The rates of nasal colonizationinthehealthcareworkerswere30.95%.ThemostcommonlydetectedsuperantigenswereSEA(31.5%), SEB (17.7%) and ETA (16.9%). The Staphylococcus aureus isolates had the highest levels of resistance against erythromycin(57.7%),clindamycin(55.4%)andco-trimoxazole(43.1%).Allisolatesweresusceptibletovancomycin,linezolid,andmupirocin. Conclusion: OurresultsrevealedthatthefrequencyofsuperantigenproducingStaphylococcusaureusisolatesis highintheMSpatients.Aswellastheseisolatesaresensitivetomupirocin.Thusitisbettertouseofmupirocin fornasaldecolonizationofStaphylococcusaureusintheMSpatients. |
| نویسنده | نفر چندم مقاله |
|---|---|
| جاوید صادقی | اول |
| ناصر علی زاده | دوم |
| مهین آهنگر اسکوئی | سوم |
| دل آرا لاغوثی | چهارم |
| داریوش سوادی اسکوئی | پنجم |
| مسعود نیکانفر | ششم |
| میرناصر سیدموسوی | هفتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Frequency of superantigen encoding genes of Staphylococcus aureus isolates.pdf | 1397/10/29 | 374444 | دانلود |
