چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Statement of the Problem: Recurrent aphthous stomatitis (RAS) is the most prevalent ulcerative condition of the oral mucosa. Many studies have emphasized on immunologic factors as the reason of inducing RAS; however, the exact etio-logic cause of RAS has not been identified yet. Vitamin D has an endocrine func-tion and regulatory effects on the immune system. It has potential therapeutic effects on autoimmune diseases, psoriasis, and neoplasms. Vitamin D deficiency has been detected in some autoimmune diseases such as rheumatoid arteritis. Purpose: The aim of the present study was to compare the serum and salivary levels of vitamin D in patients with RAS and healthy individuals. Materials and Method: In this cross sectional study, patients with RAS, refer-ring to the Department of Oral Medicine, Tabriz Faculty of Dentistry, were eval-uated after taking medical history, clinical examinations, and completing an in-formed consent form. The serum and salivary vitamin D levels were compared between case (n=26) and control (n=26) groups. Results: The mean serum vitamin D levels in the case and control groups were 33.0.7±12.41 and 50.89±9.30 (ng/dL), respectively, with a statistically significant difference (p< 0.001). On the other hand, the mean salivary vitamin D levels in the case and control groups were 17.36± 8.01 and 20.79±6.31 (ng/dL), respec-tively, with no statistically significant difference (p= 0.09). In addition, the corre-lation between the serum and salivary levels of vitamin D was 56%, being statis-tically significant (p< 0.001). Conclusion: The serum levels of vitamin D in patients with RAS were signifi-cantly less than that in healthy individuals; however, there were no significant differences in salivary vitamin D levels between patients with RAS and healthy individuals. In addition, there was a significant and positive correlation between serum and salivary levels of vitamin D in all patients. |
| نویسنده | نفر چندم مقاله |
|---|---|
| آیلا بهرامیان | اول |
| پریسا فلسفی | دوم |
| میلاد غنی زاده | چهارم |
| مریم کوه سلطانی | هفتم |
| فاطمه دباغی تبریز | نهم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| article-331-1057273.pdf | 1397/10/26 | 311981 | دانلود |
