چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Research in Molecular Medicine (RMM) Volume 6, Issue no. 1, DOI 10.18502/rmm.v6i1.3931 Production and Hosting by Knowledge E Research Article Different Features of Escherichia coli and Klebsiella pneumoniae in Children and Adults Vajihe Sheikhalizadeh1, Mohammad Ahangarzadeh Rezaee2, Nastaran Langarizadeh3, and Hamid Reza Goli4 1PhD Fellow, Department of Medical Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran 2Associate Professor, Immunology Research Center and Department of Medical Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran 3Nastaran Langarizadeh, PhD student, Department of Biotechnology, Ege University, Izmir, Turkey 4Hamid Reza Goli, Assistant Professor, Department of Medical Microbiology and Virology, Mazandaran University of Medical Sciences, Sari, Iran Abstract Introduction: This study aimed to describe the association between age groups and antimicrobial susceptibility patterns, as well as integron presence in Escherichia coli and Klebsiella pneumoniae isolates from Tabriz, Iran. Materials and methods: Equal numbers of isolates from adults and children, 140 for E. coli and 150 for K. pneumoniae, were examined for susceptibility to 13 routine antibiotics. Integron existence in multidrug resistant (MDR) isolates was also determined using PCR-RFLP. Results: Significant age-related differences were observed in the resistance rates of K. pneumoniae toward cotrimoxazol, nalidixic acid, ciprofloxacin, and norfloxacin. For E. coli, age-related differences in the resistance rates to tetracycline, chloramphenicol, ciprofloxacin, and norfloxacin were significant. PCR-RFLP results revealed the pres- ence of class 1 integron (intI1) in 24.5% and 19.2% of MDR E. coli in children and adults, respectively. In K. pneumoniae, 72.9% of isolates from children and 84% from adults were positive for intI1. The prevalence of class 2 integrons was significantly associated with age, in both E. coli and K. pneumoniae. No class 3 integrons were detected in this study. |
| نویسنده | نفر چندم مقاله |
|---|---|
| محمد آهنگرزاده رضایی | دوم |
| وجیهه شیخ علیزاده | اول |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Res Mol Me-v6n1p30-en.pdf | 1401/04/07 | 377857 | دانلود |
