ارتباط بین سطح سرمی آنتی بادی ضد توکسوپلاسما گوندی و خطر دیابت
The Correlation between Serum Levels of Anti-Toxoplasma gondii Antibodies and the Risk of Diabetes
نویسندگان: مریم خلیلی , محمود محامی اسکوئی , عباس شهبازی سیاه اسطلخی , عبدالرسول صفائیان , نادر محمدزاده , لیلا محامی اسکوئی
کلمات کلیدی: Diabetes mellitus,
Toxoplasma gondii,
Chemiluminescence,
Immunoassay
نشریه: 16582 , 4 , 13 , 2018
| نویسنده ثبت کننده مقاله |
محمود محامی اسکوئی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات ایمونولوژی |
| کد مقاله |
65513 |
| عنوان فارسی مقاله |
ارتباط بین سطح سرمی آنتی بادی ضد توکسوپلاسما گوندی و خطر دیابت |
| عنوان لاتین مقاله |
The Correlation between Serum Levels of Anti-Toxoplasma gondii Antibodies and the Risk of Diabetes |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Short Communication |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Background: This study investigated the presence of specific antibodies against
Toxoplasma gondii infection among people with diabetes (type I and II) in comparison
with control group.
Methods: Overall 300 serum samples were collected equally from three groups
including patients with type I and type II diabetes and non-diabetic healthy control
that referred to Tabriz Central Laboratory in northwest Iran during July to Sep 2015.
The level of specific IgG and IgM antibodies against T. gondii were measured using the
chemiluminescence immunoassay (CLIA) method. Chi-square and One-Way
ANCOVA were used for data analysis.
Results: Overall, 300 samples from diabetic patients (type I and type II) and control
group were examined and results showed 3, 8 and 2 cases were seropositive for anti-
T. gondii IgM respectively. Anti- T. gondii IgG seropositivity in type I and type II
diabetes and control groups were 69%, 63% and 59% respectively. We did not
observe any statistical differences among all studied groups in terms of toxoplasmosis.
There was no statistically significant relationship between all variables and
seropositivity for anti-T. gondii antibodies in type I and II diabetes and non-diabetic
groups.
Conclusion: Although there was no statistically significant relationship between
diabetes and toxoplasmosis further investigations especially experimental studies using
animal models are needed. Furthermore, these findings would not be contrary to the
need for healthcare in order to the prevention of infectious disease in diabetic patients. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| The Correlation between Serum Levels of Anti-Toxoplasma gondii Antibodies and the Risk of Diabetes.pdf | 1397/10/10 | 355095 | دانلود |