Parathyroid hormone or fibroblast growth factor 23? Which one is the main determinant of the hypophosphatemia after kidney transplantation?
Parathyroid hormone or fibroblast growth factor 23? Which one is the main determinant of the hypophosphatemia after kidney transplantation?
نویسندگان: سیدصدرالدین راثی هاشمی , امیر قربانی حق جو , مرتضی قوجازاده , جلال اعتمادی خیاوی , سیما عابدی آذر , زهرا نوارباف محمدی
کلمات کلیدی: Fibroblast growth factor 23
Parathyroid hormone
Hypophosphatemia
Kidney transplantation
Mineral and bone disorder
Chronic kidney disease
Glomerular filtration rate
نشریه: 0 , 2 , 8 , 2019
| نویسنده ثبت کننده مقاله |
سیدصدرالدین راثی هاشمی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کلیه |
| کد مقاله |
65210 |
| عنوان فارسی مقاله |
Parathyroid hormone or fibroblast growth factor 23? Which one is the main determinant of the hypophosphatemia after kidney transplantation? |
| عنوان لاتین مقاله |
Parathyroid hormone or fibroblast growth factor 23? Which one is the main determinant of the hypophosphatemia after kidney transplantation? |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
Journal of renal injury prevention |
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Introduction: Kidney transplantation restores many of the disorders accompanying endstage
renal disease (ESRD). However, hypophosphatemia is common complication after
renal transplantation. High levels of fibroblast growth factor 23 (FGF23) and parathyroid
hormone (PTH) are two suspected factors determining the hypophosphatemia after kidney
transplantation.
Objectives: This observational prospective study was carried out to clarify the role of
mentioned factors in hypophosphatemia after kidney transplantation.
Patients and Methods: Living donor kidney transplant recipients which admitted to the
ward of the renal transplantation, enrolled to the study. Parameters of bone and mineral
metabolism including FGF23 and intact PTH levels were assessed.
Results: High FGF23 level before transplantation was related to lower phosphate levels at 3rd
month after transplantation. PTH levels showed no relationship with hypophosphatemia
after kidney transplantation.
Conclusion: High levels of FGF23 in ESRD patients undergoing kidney transplantation is an
important determinant of hypophosphatemia in long-term follow up. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Parathyroid hormone.pdf | 1399/05/12 | 435765 | دانلود |