Vitamin D deficiency and functional response to CRT in heart failure patients.
Vitamin D deficiency and functional response to CRT in heart failure patients.
نویسندگان: احمد سپرهم , لیلی پورافکاری , بابک کاظمی اربط , فریبرز اکبرزاده , مهرنوش طوفان تبریزی , حسین ساطع , یوسف حقی زاده
کلمات کلیدی: Systolic heart failure · Cardiac resynchronization
therapy · Myocardial remodeling ·
Ventricular end-systolic volume · 6-Minute
Walk Test
نشریه: 13680 , 42 , 5 , 2017
| نویسنده ثبت کننده مقاله |
احمد سپرهم |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات قلب وعروق |
| کد مقاله |
65205 |
| عنوان فارسی مقاله |
Vitamin D deficiency and functional response to CRT in heart failure patients. |
| عنوان لاتین مقاله |
Vitamin D deficiency and functional response to CRT in heart failure patients. |
| ناشر |
8 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Background. Vitamin D deficiency has been
associated with a poor outcome in patients
with heart failure (HF). We examined the role
of vitaminDin the response ofHF patients to
cardiac resynchronization therapy (CRT).
Methods. The study comprised 50 patients
(30 men and 20 women) with HF undergoing
CRT implantationwho were prospectively
enrolled. Response to CRT was defined as
a combination of ≥15% reduction in left
ventricular end-systolic volume (LVESV) and
≥10% improvement in the 6-Minute Walk
Test within 6 months. Patients were grouped
based on their levels of vitamin D prior to CRT
implantation. Clinical and echocardiographic
examinations were performed prior to and
6 months after the procedure.
Results. Of the patients, 11 (22%) failed to
respond to CRT; two patients died within
6 months and an additional nine patients
showed no improvement in the 6-Minute
Walk Test and no reduction in their baseline
LVESV. A comparison was made between
25 patients with sufficient levels of vitamin D
and 25 patients with insufficient levels. Nine
patients (36%) in the “insufficient” group and
two patients (8%) in the “sufficient” group
failed to respond to CRT implantation (p =
0.037).
Conclusion. Adequate serum concentrations
of vitamin D play a significant role in
improving the functional status of patients
with systolic HF following CRT implantation. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| hagizade paper.pdf | 1397/09/11 | 768917 | دانلود |