Effect of vitamin D treatment in children with attention-deficit hyperactivity disorder
Effect of vitamin D treatment in children with attention-deficit hyperactivity disorder
نویسندگان: نادیا دهبکری , سید غلامرضا نورآذر , آیدا غفاری , گیتا مهدی زاده , پروین سربخش , صبا غفاری
کلمات کلیدی: Attention-defcit hyperactivity disorder · Children · Conners parent rating scale · Vitamin D
نشریه: 35035 , 1 , 15 , 2018
| نویسنده ثبت کننده مقاله |
صبا غفاری |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کاربردی دارویی |
| کد مقاله |
65099 |
| عنوان فارسی مقاله |
Effect of vitamin D treatment in children with attention-deficit hyperactivity disorder |
| عنوان لاتین مقاله |
Effect of vitamin D treatment in children with attention-deficit hyperactivity disorder |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Background In this research the symptom improvement of attention-defcit hyperactivity disorder (ADHD) of children was
assessed by oral vitamin D administration in Tabriz, Iran.
Methods In this double-blind, randomized clinical trials, 96 children (2–18 years) were enrolled to placebo and vitamin D
groups. Children took vitamin D pearl (50,000 IU/week) or placebo for 6 weeks. Children, who had the change in methylphenidate dosage and received any anticonvulsants and corticosteroids were excluded from the research. ADHD symptoms
were diagnosed by Conners parent rating scale (CPRS) test at baseline and after intervention. ADHD Conners divided into
inattention (IA), hyperactivity/impulsivity (H/I) and combination type (C) subscales. Vitamin D serum level was assessed
at baseline and after 8 weeks in both groups.
Results The diferences between CPRS and its subscales were not signifcant at baseline (P > 0.05). The Conners IA score
was decreased in vitamin D group (P < 0.05; adjusted with age and baseline values). ADHD Conners and all subscale scores
reduced remarkably after intervention in patients with insufcient level of vitamin D compared to placebo (P < 0.05).
Conclusions Oral vitamin D improved ADHD symptoms with a particular efect on inattention symptoms. In addition,
symptoms related to all subscales were improved remarkably in patients with insufcient level of vitamin D. Vitamin D
treatment in children with ADHD could be considered due to the expand beneft of vitamin D in body. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Dehbokri2018_Article_EffectOfVitaminDTreatmentInCh1i.pdf | 1397/12/11 | 974929 | دانلود |