| ABSTRACT: Phytochemicals are good sources of natural antioxidants and have beneficial effects
on human health. Many of phenolic phytochemicals have shown antimicrobial and antifungal activity.
Anise hyssop (Agastache foeniculum [Pursh] Kuntze) is a perennial aromatic plant of the
Lamiaceae family with antimicrobial and antifungal properties and useful for gastrointestinal problems.
In this investigation, the antioxidant activity of extracts, their antimicrobial activity against
Staphylococcus aureus, Listeria monocytogenes, Bacillus cereus, B. subtilis, Salmonella thyphimurium,
S. enteritidis, Escherichia coli strains and their antifungal activity against Aspergillus
niger and A. flavus was evaluated. Seven components were identified, representing 95.4% of the
oils including methyl chavicol (83.1%), limonene (3.4%), spathulenol (3.1%) and caryophyllene
oxide (3.1%). Agar disk diffusion and broth micro-well dilution assays showed that B. subtilis was
the most resistant strain against both of the EOs and E. coli was the most sensitive bacteria. Results
of both disc diffusion and MIC showed that the EO was more effective against A. flavus than
A. niger. Antioxidant activity of A. foeniculum by DPPH and ABTS assays revealed remarkable
antioxidant activities of this EO comparing with BHT. Results of current study indicated that A.
foeniculum EOs can be used as a food preservative in having antibacterial, antifungal and antioxidant
activity for the control of food deterioration. |