Pectin-whey protein complexes vs. small molecule surfactants for stabilization of double nano-emulsions as novel bioactive delivery systems

Pectin-whey protein complexes vs. small molecule surfactants for stabilization of double nano-emulsions as novel bioactive delivery systems


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دانشگاه علوم پزشکی تبریز
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نویسندگان: حامد همیشه کار , عزیز همایونی راد

کلمات کلیدی: NanoemulsionsDouble emulsionsWPCPectinGallic acidTween 80

نشریه: 20229 , 245 , 245 , 2019

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نویسنده ثبت کننده مقاله حامد همیشه کار
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات کاربردی دارویی
کد مقاله 64707
عنوان فارسی مقاله Pectin-whey protein complexes vs. small molecule surfactants for stabilization of double nano-emulsions as novel bioactive delivery systems
عنوان لاتین مقاله Pectin-whey protein complexes vs. small molecule surfactants for stabilization of double nano-emulsions as novel bioactive delivery systems
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Water-in-oil-in-water (W1/O/W2) double emulsions are one of the most efficient nutraceutical delivery systems. Our main objective was to compare some emulsion properties of double nano-emulsions loaded with gallic acid in W1 phase. Polyglycerol polyricinoleate (PGPR), and pectin-WPC or/Tween 80 were applied as emulsifiers in W1-O and O-W2 interfaces, respectively. Our results revealed that complex of pectin-WPC had the same resistance against sedimentation and creaming as Tween 80. The particle size of double emulsions produced by Tween 80 and pectin-WPC were in the range of 98–577 and 100–1520 nm, respectively. Z-potential of double emulsions prepared with pectin-WPC were more negative than −30 mV; so they were more stable during the long term storage. The optimum conditions for preparing WPC-pectin stabilized delivery systems were determined as 5, 75 and 20 (wt. %) PGPR, soybean oil and deionized water, respectively for internal W1/O nano-emulsion; and 1, 4, 79 and 16 (wt. %) pectin, WPC, deionized water, and internal nano-emulsion, respectively for the W1/O/W2 emulsions. Student's t-test analysis revealed that except for z-potential, there were no significant differences between emulsifiers (pectin-WPC and Tween 80). The present study demonstrates that pectin-WPC complex can be used as an appropriate emulsifier comparable with Tween 80 for stabilizing double emulsions.

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نویسنده نفر چندم مقاله
حامد همیشه کارسوم
عزیز همایونی رادچهارم

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نام فایل تاریخ درج فایل اندازه فایل دانلود
2019-Gharehbeglou-Journal of Food Engineering.pdf1397/08/191912279دانلود