Is fish oil supplementation effective on maternal serum FBS, oral glucose tolerance test, hemoglobin and hematocrit in low risk pregnant women? A triple-blind randomized controlled trial

Is fish oil supplementation effective on maternal serum FBS, oral glucose tolerance test, hemoglobin and hematocrit in low risk pregnant women? A triple-blind randomized controlled trial


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دانشگاه علوم پزشکی تبریز
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نویسندگان: حسین اصلانی , لیلا واحدی , علیرضا استاد رحیمی , عزیزه فرشباف خلیلی

کلمات کلیدی: fasting blood sugar; fish oil supplements; hematocrit; hemoglobin; oral glucose tolerance test; pregnant women

نشریه: 55296 , 3 , 15 , 2018

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نویسنده ثبت کننده مقاله حسین اصلانی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه تیم های تحقیقاتی دانشگاه
کد مقاله 64645
عنوان فارسی مقاله Is fish oil supplementation effective on maternal serum FBS, oral glucose tolerance test, hemoglobin and hematocrit in low risk pregnant women? A triple-blind randomized controlled trial
عنوان لاتین مقاله Is fish oil supplementation effective on maternal serum FBS, oral glucose tolerance test, hemoglobin and hematocrit in low risk pregnant women? A triple-blind randomized controlled trial
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – Medline
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background Fish oil contains polyunsaturated fatty acids including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) which were considered as essential fatty acids. The purpose of present study was to evaluate the effects of fish oil supplementation on maternal serum fasting blood sugar (FBS), oral glucose tolerance test (OGTT), hemoglobin (Hb), and hematocrit (Hct). Methods In this randomized triple-blind clinical trial, 150 pregnant women were allocated into two groups randomly. In the intervention group, women received one fish oil capsule daily (1,000 mg consisted of 120 mg DHA and 180 mg EPA), and control group received placebo from the end of twentieth week of pregnancy until delivery (140 capsules). FBS, 2-hour 75 g OGTT, Hb, and Hct were measured at 6–10 and 26–30 weeks of pregnancy. Analysis was based on intervention to treat. Results At the weeks 26–30, mean FBS in the intervention and control groups were 76.92 (9.8) and 75.64 (8.2) mg/dl, respectively [adjusted mean difference (aMD) (95% CI):1.46 (−2.13 to 5.05)]. Also, there was no significant difference between two groups in 2-hour OGTT [aMD (95% CI): −4.69 (−13.75 to 4.52)]. Mean (SD) Hb was 11.8 (1.1) versus 11.8 (0.7) g/dl in the intervention and control groups, respectively [aMD (95% CI): 0.001 (−0.328 to 0.330)], mean (SD) Hct were 36.12% (2.8%) and 35.84% (2.3%), respectively [aMD (95% CI): 0.25 (−0.65 to 1.14)]. Conclusions Based on the findings of present study, fish oil supplementation has no significant effect on Hb, Hct, FBS and 2-hour OGTT of pregnant women.

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نویسنده نفر چندم مقاله
حسین اصلانیچهارم
لیلا واحدیاول
علیرضا استاد رحیمیدوم
عزیزه فرشباف خلیلیپنجم

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