| One of the useful and popular molecular methods is polymerase chain reaction (PCR). However, PCR
method was still recurrently impaired by its poor sensitivity, low specificity, false positive results, etc. To
improve both productivity and quality of PCR, nanomaterials such as carbon nanomaterials, metal
nanoparticles, quantum dots and nano metal oxide have been added into PCR reaction. Nanoparticle
assisted PCR (NanoPCR) has received great attention because of its exceptional selectivity, sensitivity and
efficiency. In this review article, it was summarized the mechanisms and advantages of the mostly utilized
nanoparticles in NanoPCR, such as carbon nanotube, gold, quantum dots, graphene, metallic oxide and
composite nanomaterial. |