چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Background and objectives: The rhizomes of Eremostachys azerbaijanica Rech. f., as an indigenous plant in East Azerbaijan province of Iran, were studied for isolation and identification of possible phytoconstituents. Methods: The air- dried and ground rhizomes were extracted with n-hexane, dichloromethane (DCM) and methanol (MeOH) using a Soxhlet apparatus. The 10%, 20% and 80% MeOH in water C18 cartridge solid phase extraction products )Sep-Pak fractions( of the MeOH extract were subjected to preparative reversed- phase high performance liquid chromatography (RPHPLC) and the isolated pure compounds were identified by one- dimensional nuclear magnetic resonance (1D - NMR) spectroscopic technique. Results: The spectroscopic data of the compounds were compared with the respective published data and the obtained results showed the presence of four pure components, 6 - Hydroxy loganin (1), Shanzhiside methyl ester (2), Eremostachiin (β-Dglucopyranosyl-(1→2)-β-D-glucopyranosyl ester of phlomisoic acid) (3) and Phlomisoside II (4), with iridoid and furano labdane- type diterpene glycoside structures. Conclusion: The occurrence of these types of chemical structures might be a confirmation to close relation and similar pharmacological and biological activities between Eremostachys and Phlomis genera. |
| نویسنده | نفر چندم مقاله |
|---|---|
| سولماز اثناعشری | اول |
| عباس دل آذر | دوم |
| صدیقه بامدادمقدم | سوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| RJP_Volume 5_Issue 3_Pages 7-13.pdf | 1397/08/13 | 639785 | دانلود |
