چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| الناز شاسب | دوم |
| صبا غفاری | سوم |
| ثمین فرخ رخ | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | NICU, DUE, vancomycin. Preterm neonate |
| خلاصه مقاله | Introduction and background: Preterm neonatal sepsis due to immature immunity and invasive procedures, is commonnd associated with high morbidity and mortality. By considering high rate of vancomycin administration and its coverage on gram positive germs, it is necessary to evaluate vancomycin usage in neonate intensive care unit (NICU). Methods. This is a retrospective study, which enrolled preterm neonates (born before 34 week gestation) who admitted to NICU of Alzahra hospital from March 2015 to March 2016. From all, 158 patients diagnosed with sepsis and received antibiotics. The demographic, dose and duration of antibiotic administration was extracted from patient document. Results: 56.3% of total deliveries were caesarean section (SC) and 43.7%were natural vaginal delivery (NVD). 75.3% were singleton, 20.3% twins and 4.4% triplet. 42.4% of neonates were female. Only in 12% CRP was positive. 87.3% were taken blood culture which 5.7% was identified Klebsiella, 1.3% Acinetobacter, 1.3% Staphylococci aureus, 0.6% candida albikenz and 1.3% entrobacter. 8.9% was taken urine culture which 0.6% identified as Klebsiella. 3.8% were CSF cultured. Selection of vancomycin in early and late onset sepsis was correct in 50% and 6.3% respectively.Furthermore, the duration of vancomycin administration in early and late onset sepsis was correct in 11.4% and 3.8% respectively. Discussion and conclussion:vancomycin should be used with caution in premature neonates. Because of potential mistakes of vancomycin administration, tight control of dosage, duration and also therapeutic drug monitoring are necessary in neonates who admitted to NICU. Furthermore, the result of this study indicates the need for presence of a clinical pharmacist in hospitals especially in intensive care unit |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| certificate.JPG | 1397/08/12 | 33424 | دانلود |
| abstract.docx | 1397/08/12 | 430181 | دانلود |
| IMG_0532.JPG | 1397/08/12 | 33424 | دانلود |
