| Background: Gastric cancer (GC) is the first and the third prevalent cancer among males and
females in Iran, respectively. The aim of this study was mainly to identify high‑risk areas of
GC by assessing the spatial and temporal pattern of incidence, and second, to explore some risk
factors of GC in ecological setting. Methods: In this cross‑sectional ecological study we used
Bayesian hierarchical space‑time model to measure the relative risk and temporal trends of GC in
Iran from 2005 to 2010 based on available data. Data analysis was done by the use of integrated
nested Laplace approximation Bayesian approach in R software. Results: Overall trend of GC
was significantly decreasing during the study period. Ardabil, Khorasan Razavi, West Azarbaijan,
Zanjan, and Mazandaran provinces had the highest risk of incidence. Overweight and smoking were
directly and significantly associated with GC risk. Conclusions: During the study period, GC has
decreased in Iran. Nevertheless, GC risk was generally high in Northern and Northwestern provinces
of Iran. Different health policies according to GC risk and trend are required for each province.
Improvements in screening and education programs and conducting further epidemiological studies
could help to reduce the incidence of GC in high risk provinces. |