Comparison of Vitamin E and L-Carnitine, Separately or in Combination in Patients With Intradialytic Complications

Comparison of Vitamin E and L-Carnitine, Separately or in Combination in Patients With Intradialytic Complications


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نویسندگان: حمید طیبی خسروشاهی , بهلول حبیبی اصل , پرستو چایچی

کلمات کلیدی: Renal Dialysis; Kidney Failure, Chronic; Vitamin E; Carnitine

نشریه: 25023 , 4 , 5 , 2013

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نویسنده ثبت کننده مقاله حمید طیبی خسروشاهی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات کلیه
کد مقاله 64410
عنوان فارسی مقاله Comparison of Vitamin E and L-Carnitine, Separately or in Combination in Patients With Intradialytic Complications
عنوان لاتین مقاله Comparison of Vitamin E and L-Carnitine, Separately or in Combination in Patients With Intradialytic Complications
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Research Letter
نحوه ایندکس شدن مقاله ایندکس شده سطح سه – Scopus
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background: The most common complications during dialysis are hypotension and muscle cramps. There are many strategies to prevent and treat these complications. Objectives: The aim of this study is to evaluate effects of vitamin E and L-carnitine supplementation alone and in combination on intradialytic complications. Patients and Methods: In a prospective study, 20 patients with end stage renal disease on chronic hemodialysis that had intradialytic complications such as hypotension, muscle cramp, nausea, vomiting and headache were studied. These patients were studied in four 45 day periods, beginning with no treatment (step 1), receiving vitamin E (200 IU/d) (step 2), receiving L-carnitine (500 mg/d) (step 3) and their combination (step 4). Intradialytic complications were recorded in each step and compared between treatments. Results: All three treatments significantly reduced frequency of muscle cramps in comparison to baseline values. Vitamin E alone and in combination with L-carnitine reduced the frequency of muscle cramps more effectively. Hypotension was significantly lower in combination therapy in comparison to baseline values and vitamin E treatment. Conclusions: Vitamin E and L-carnitine both have comparative effects on intradialytic complications. As the combination use of vitamin E and L-carnitine could more effectively reduce the intradialytic complications, it is recommended for daily use in hemodialysis patients.

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نویسنده نفر چندم مقاله
حمید طیبی خسروشاهیاول
بهلول حبیبی اصلدوم
پرستو چایچیچهارم

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نام فایل تاریخ درج فایل اندازه فایل دانلود
2013.pdf1397/08/0778688دانلود