چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| In the present work, a simultaneous derivatization and aireassisted liquideliquid microextraction method based on the solidification of deep eutectic solvent coupled with gas chromatographyemass spectrometry has been developed for the determination of some aromatic amines in various aqueous samples. In this work, choline chloride and nebutyric acid are mixed at a suitable molar ratio and after heating, a deep eutectic solvent of low density compared to water is formed. The prepared extraction solvent is mixed with ethyl chloroformate as a derivatization agent and injected into an alkaline aqueous solution containing the target analytes adjusted at elevated temperature. The resulting mixture is drawn into a syringe via a needle and pushed out into a test tube several times. As a result, a cloudy solution consisting of the fine droplets of the extraction solvent containing the derivatized aromatic amines is obtained. Then, the solution is placed into an ice bath and the extraction solvent is solidified and collects on the top of the solution after centrifugation. Then the solidified extraction solvent is removed by a spatula and transferred to a microtube and dissolved in 10 mL acetonitrile. A portion of the obtained mixture is injected into the gas chromatographyemass spectrometry. Under optimum conditions, limits of detection and quantification were obtained in the ranges of 1.8e6.0, and 6.0e23 ng L1, respectively. The extraction recoveries, enhancement factors, and enrichment factors of the selected aromatic amines ranged from 79e94%, 2498e3422 and 790e940, respectively. The relative standard deviations were 5.3% for intrae (n ¼ 6) and intereday (n ¼ 4) precisions at a concentration of 100 ng L1 of each analyte. |
| نویسنده | نفر چندم مقاله |
|---|---|
| محمدرضا افشار مقدم | چهارم |
| محمدعلی تربتی | اول |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| ACA.pdf | 1397/08/07 | 1008390 | دانلود |
