The use of chitosan as a bioactive polysaccharide in non-invasive detection of malondialdehyde biomarker in human exhaled breath condensate: A new platform towards diagnosis of some lung disease
The use of chitosan as a bioactive polysaccharide in non-invasive detection of malondialdehyde biomarker in human exhaled breath condensate: A new platform towards diagnosis of some lung disease
نویسندگان: محمد حسن زاده محله , ابوالقاسم جویبان
کلمات کلیدی: Bioactive polysaccharide, Malondialdehyde, Oxidative stress, Lipid peroxidation, Biomarker analysis
نشریه: 15718 , 01 , 120 , 2018
| نویسنده ثبت کننده مقاله |
محمد حسن زاده محله |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کاربردی دارویی |
| کد مقاله |
64377 |
| عنوان فارسی مقاله |
The use of chitosan as a bioactive polysaccharide in non-invasive detection of malondialdehyde biomarker in human exhaled breath condensate: A new platform towards diagnosis of some lung disease |
| عنوان لاتین مقاله |
The use of chitosan as a bioactive polysaccharide in non-invasive detection of malondialdehyde biomarker in human exhaled breath condensate: A new platform towards diagnosis of some lung disease |
| ناشر |
4 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Herein, a reusable and time-saving strategy for the electrochemical polymerization of dopamine (EPD) is reported. In this work, biocompatible polymer chitosan (CS) was electrodeposited on the surface of PDA modified glassy carbon electrode. Owing to the abundant catechol and amine groups in the PDA layer, uniform silver nanoparticles (Ag NPs) are deposited onto the POLY(DA-CS) and can effectively prevent the recombination of electron-hole pairs generated from photo-electrocatalysis and transfer the captured electrons to participate in the photo-electrocatalytic reaction process. Compared with pristine POLY(DA-CS), the as-prepared POLY(DA-CS)-AgNPs organic-inorganic hybrid exhibit electrochemical sensitivity for detecting MDA and display excellent durability. Furthermore, the mussel-inspired electropolymerization strategy and the fast EPD-Ag nanoparticle decorating process presented herein can be readily extended to various biomedical analysis and lung cancer detection. It is the adaptation of the established POLY(DA-CS)-Ag NPs organic-inorganic hybrid for a selective, robust, and generalizable sensing system that is the emphasis of this work. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 1.pdf | 1397/08/05 | 8220254 | دانلود |