| Abstract
Background:
Cardiovascular disease (CVD) is the leading cause of mortality among men and
women around the world. The aim of this study was to investigate major cardiovascular risk
factors in women living in the Tabriz petrochemical region, Iran during spring 2017.
Methods:
In this cross-sectional study, a sample of 152 women aged 30-55 years was selected
from who attended health center in Tabriz, Iran. Anthropometric measurements, blood pressure,
daily dietary intakes and fasting serum lipid profile, oxidized LDL (ox-LDL) and high sensitivity
C-reactive protein (hs-CRP) were evaluated.
Results:
The prevalence of overweight, general and abdominal obesity (based on Body mass index
[BMI] and waist circumference [WC]) was 34.2%, 52.6%, and 73.7%, respectively. Eleven point
two percent and 4.6% of women had pre-hypertension based on systolic blood pressure (SBP)
and diastolic blood pressure (DBP). High serum triglyceride (TG), total cholesterol (TC), low-
density lipoprotein cholesterol (LDL-C) and low high-density lipoprotein cholesterol (HDL-C)
were determined in 32.5%, 25.7%, 17.8% and 56.6% of subjects, respectively. The median of
serum ox-LDL concentration was 3181.5 ng/L. Sixty-five point eight percent of participants had
high hs-CRP levels. In the multiple-adjusted quintile regression analysis, significant relationships
were found between serum ox-LDL and age (B = 96.7,
P
= 0.003) and between serum hs-CRP
with diastolic blood pressure (B = 0.1,
P
= 0.083) and TG (B = 0.01,
P
= 0.088).
Conclusion:
The high prevalence of cardiovascular risk factors in the studied women warrants
more public health attention. The results also suggest that aging was associated with high serum
ox-LDL and increased serum hs-CRP levels, which may reflect enhanced DBP and serum TG. |