| Background: Given the importance of having valid information about the prevalence and reasons of
self-medication among pregnant women for preventing self-medication during this period, this study
aimed to systematically review and perform a meta-analysis on the prevalence and reasons of selfmedication
during pregnancy.
Methods: This systematic review and meta-analysis was conducted in 2018 to estimate the overall
self-medication prevalence based on the database sources PubMed, Scopus, Google Scholar, MagIran,
IranMedex and SID. Required data were collected using keywords: medication, self-medication, overthe-counter,
non-prescription, prevalence, etiology, and occurrence and pregnant. Descriptive and crosssectional
studies in English and Persian languages were included. There was no time limitation for search. R
software was applied for meta-analysis. Random-effects model was applied to estimate the self-medication
prevalence with 95% confidence interval. Q statistics and I2
were used to measure the heterogeneity.
Results: Out of 490 retrieved articles, finally 13 studies were included in meta-analysis, 6 studies
of which reported the cause of self-medication. The overall estimated prevalence of self-medication
based on the random effect model was 32% (95% CI, 22% -44% ). The most important reasons of selfmedication
were previous experience of the disease. The most important group of disease in which
patients self-medicated was anemia. Also, the most important group of medication was herbal.
Conclusion: The results of this study showed that the prevalence of self-medication among pregnant women
was relatively high and required effective interventions to reduce and prevent self-medication among this
group. Providing required information and raising awareness about complications resulting from selfmedication,
in particular herbal medicines and dietary supplements, should be taken into account. |