Lactobacillus intake for 60 days favors antioxidant status of human breast milk: an RCT

Lactobacillus intake for 60 days favors antioxidant status of human breast milk: an RCT


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دانشگاه علوم پزشکی تبریز

نویسندگان: رضا مهدوی , لیلا نیک نیاز , علیرضا استاد رحیمی , زینب نیک نیاز , ژیلا خامنیان

کلمات کلیدی: lactobacillus, breast milk, total antioxidant capacity (TAC), malondialdehyde (MDA), trend

نشریه: 3498 , 4 , 26 , 2017

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مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات مدیریت خدمات بهداشتی درمانی تبریز
کد مقاله 64198
عنوان فارسی مقاله Lactobacillus intake for 60 days favors antioxidant status of human breast milk: an RCT
عنوان لاتین مقاله Lactobacillus intake for 60 days favors antioxidant status of human breast milk: an RCT
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background and Objectives: This study aimed to evaluate the effects of lactobacillus supplementation on trends of breast milk antioxidant parameters. Methods and Study Design: In an interventional study, 50 lactating women were randomly allocated to receive a daily supplement of lactobacillus (n=25) or a placebo (n=25) for 60 days. Daily dietary intake, anthropometric measures and breast milk antioxidant parameters were determined at the onset, and days 30 and 60 of the study. Repeated-measures ANOVA were performed to assess the change over time in the anthropometric and biochemical parameters between the two groups. The main effect of treatment was compared by using Bonferroni’s procedure for CI adjustment. The significance level was set at p<0.05. Results: There was a significant increase in breast milk total antioxidant capacity (TAC) between onset of study and day 30 (p=0.01) and day 60 (p=0.001) after lactobacillus supplementation; however, breast milk TAC level did not change significantly between days 30 and 60 (p=0.7). In the placebo group, breast milk TAC levels decreased significantly after 60 days (p=0.001). Breast milk malondialdehyde (MDA) levels decreased progressively during the study in the lactobacillus group (p=0.001); however, there was a significant increase in MDA with time in breast milk samples in the placebo group (p=0.015). Conclusions: Based on the findings, lactobacillus supplementation for 60 days could significantly increase breast milk TAC and decrease breast milk MDA levels, compared with baseline; however, further studies are needed to confirm these results.

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نویسنده نفر چندم مقاله
رضا مهدویاول
لیلا نیک نیازدوم
علیرضا استاد رحیمیسوم
زینب نیک نیازچهارم
ژیلا خامنیانپنجم

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Lactobacillus intake for 60 days.pdf1397/07/25393659دانلود