Determining the Risk of Intra-Comm unity Transmission of Tuberculosis in the Northwest of IranThrough 15 Loci Miru-Vntr Typing
Determining the Risk of Intra-Community Transmission of Tuberculosis in the Northwest of Iran Through 15 Loci Miru-Vntr Typing
نویسندگان: سید رضا مودب , خلیل انصارین
کلمات کلیدی: tuberculosis, molecular epidemiology, 15 loci MIRU-VNTR, intra-community transmission, recent transmission
نشریه: 39483 , 27 , 7 , 2017
| نویسنده ثبت کننده مقاله |
سید رضا مودب |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پیراپزشکی |
| کد مقاله |
63606 |
| عنوان فارسی مقاله |
Determining the Risk of Intra-Comm unity Transmission of Tuberculosis in the Northwest of IranThrough 15 Loci Miru-Vntr Typing |
| عنوان لاتین مقاله |
Determining the Risk of Intra-Community Transmission of Tuberculosis in the Northwest of Iran Through 15 Loci Miru-Vntr Typing |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| This study was carried out in order to investigating the effect of travelling on the transmission of tuberculosis from high- to lowburden
TB countries. Mycobacteria samples isolated from patients of distinct and relatively co-related countries (Azerbaijan
Republic and Tabriz [located in the northwest of Iran]) were analyzed through 15 loci MIRU-VNTR typing method. PCR was done
using special primers for each of the loci; then the number of allele repeats for all loci were determined by the size of their fragments.
Finally, the created numeric patterns for each isolate were analyzed and clustered, using MIRU-VNTRplus.org website. All
119 isolates dispersing at 106 distinct patterns were composed of 10 clusters with 23 members and 96 unique patterns. Nine and five
loci had high and moderate discriminatory power, respectively, but only one of them was poor in clustering. The study showed that
89.08% of TB cases involved resulted from the reactivation pattern and 10.92% were related to ongoing transmission. Although
Azerbaijan Republic is a higher-burden TB region than Tabriz and Azerbaijan people make frequent tours to Tabriz to receive low
or free medical services, the findings showed no TB transmission from the regions at least during the year of the study. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| DETERMINING THE RISK OF INTRA-COMMUNITY TRANSMISSION.pdf | 1397/05/17 | 519987 | دانلود |